Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 10/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | NPY4R | P50391 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29163541 | 0.88 | LMNA (0.41) | SMN1; SMN2LMNANPY1RNPY2RNPY4R | |
| SCHEMBL29164081 | 0.88 | IDE (0.43) | SMN1; SMN2RAB9AGAAEPHX1NPY1R | |
| SCHEMBL8342382 | 0.82 | MEN1 (0.43) | SMN1; SMN2LMNARAB9ANPC1GAA | |
| SCHEMBL29164082 | 0.82 | F2 (0.43) | RAB9ANPC1NPY1RNPY2RNPY4R | |
| SCHEMBL8341764 | 0.81 | NPY4R (0.47) | LMNADPP8DPP9DPP7EPHX1 | |
| SCHEMBL27352129 | 0.81 | NPY4R (0.47) | LMNADPP8DPP9DPP7EPHX1 | |
| Hydrochloric Acid SCHEMBL28274785 | 0.81 | MEN1 (0.43) | SMN1; SMN2LMNARAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL28274778 | 0.81 | MEN1 (0.43) | SMN1; SMN2LMNARAB9ANPC1GAA | |
| Pabetan SCHEMBL14928984 | 0.79 | NPY4R (0.46) | EPHX1NPY1RNPY2RNPY4RNPY5R | |
| Pabetan SCHEMBL4546522 | 0.79 | NPY4R (0.46) | EPHX1NPY1RNPY2RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486762-A | Novel compound and use method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-02-02 | — | — | CN | disclosed |