SCHEMBL2916359

SCHEMBL2916359

CN1CCCN(CCN)CC1

nearest known ligand 0.76

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.62
CHKA P35790 4/20 0.52
CA2 P00918 1/20 0.52
NCF1 P14598 1/20 0.52
PRMT6 Q96LA8 1/20 0.52
SIGMAR1 Q99720 2/20 0.42
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL42017 0.90 ALOX15 (0.77) ALOX15CHKACA2NCF1PRMT6
SCHEMBL7530875 0.90 ALOX15 (0.77) ALOX15CHKACA2NCF1PRMT6
SCHEMBL10685407 0.90 ALOX15 (0.77) ALOX15CHKACA2NCF1PRMT6
Hydrochloric Acid SCHEMBL1934087 0.87 ALOX15 (0.72) ALOX15CHKACA2NCF1PRMT6
Hydrochloric Acid SCHEMBL3668489 0.87 ALOX15 (0.72) ALOX15CHKACA2NCF1PRMT6
Hydrochloric Acid SCHEMBL6898782 0.87 ALOX15 (0.72) ALOX15CHKACA2NCF1PRMT6
SCHEMBL22691893 0.87 ALOX15 (0.81) ALOX15CHKACA2NCF1PRMT6
SCHEMBL3964262 0.86 CHKA (0.49) ALOX15CHKACA2NCF1PRMT6
Hydrochloric Acid SCHEMBL3671864 0.85 ALOX15 (0.77) ALOX15CHKACA2NCF1PRMT6
SCHEMBL27250180 0.85 CHKA (0.52) CHKACA2NCF1PRMT6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406439-B Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-10-18 CN claimed
CN-118406439-A Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-07-30 CN claimed
CN-115093794-B Polysilicon polishing composition and application thereof 万华化学集团电子材料有限公司 2023-10-13 CN claimed
CN-118406439-B Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-10-18 CN disclosed
CN-118406439-A Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-07-30 CN disclosed
EP-4400107-A1 IONIZABLE LIPOSOME, PREPARATION THEREOF, AND APPLICATION THEREOF IN GENE DELIVERY Maxirna (Zhejiang) Technology Co., Ltd. (CN) 2024-07-17 EP disclosed
CN-115093794-B Polysilicon polishing composition and application thereof 万华化学集团电子材料有限公司 2023-10-13 CN disclosed
US-11731986-B2 Inhibitors of low molecular weight protein tyrosine phosphatase (LMPTP) and uses thereof Sanford Burnham Prebys Medical Discovery Institute (US) 2023-08-22 US disclosed
US-11731986-B2 Inhibitors of low molecular weight protein tyrosine phosphatase (LMPTP) and uses thereof Sanford Burnham Prebys Medical Discovery Institute (US) 2023-08-22 US disclosed
US-11731986-B2 Inhibitors of low molecular weight protein tyrosine phosphatase (LMPTP) and uses thereof Sanford Burnham Prebys Medical Discovery Institute (US) 2023-08-22 US disclosed
WO-2023133089-A1 IONIZABLE LIPIDS FOR MULTIPLE ORGAN TARGETING MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-07-13 WO disclosed
EP-1803719-A1 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-07-04 EP disclosed
EP-1785418-A1 PYRAZOLE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-05-16 EP disclosed
EP-1762568-A1 PYRAZOLE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-03-14 EP disclosed
US-20060189591-A1 Five-membered heterocyclic derivative DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-08-24 US disclosed
US-20060128685-A1 Pyrazole derivative DAIICHI PHARMACEUTICAL CO., LTD., (JP) 2006-06-15 US disclosed
CN-1774435-A 5-membered heterocyclic derivative DAIICHI SEIYAKU CO (JP) 2006-05-17 CN disclosed
CN-1759110-A Pyrazole derivatives DAIICHI SEIYAKU CO (JP) 2006-04-12 CN disclosed
EP-1621537-A1 FIVE-MEMBERED HETEROCYCLIC DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-02-01 EP disclosed
EP-1591443-A1 PYRAZOLE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128685-A1 Pyrazole derivative PTGS1, PTGS2, PTGER1 ALOX15 39/4885CHKA 3895/4885CA2 294/4885
US-11731986-B2 Inhibitors of low molecular weight protein tyrosine phosphatase (LMPTP) and uses thereof ACP1, PTPRCAP, PTPRO ALOX15 4068/4885CHKA 1892/4885CA2 3352/4885
US-20060189591-A1 Five-membered heterocyclic derivative PTGS1, PTGIS, PTGS2 ALOX15 36/4885CHKA 4504/4885CA2 126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.