Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18528976 | 0.79 | JAK2 (0.31) | JAK2JAK1TYK2JAK3CD274 | |
| SCHEMBL569695 | 0.74 | — | — | |
| SCHEMBL27091416 | 0.73 | NPC1 (0.40) | JAK2JAK1TYK2JAK3CD274 | |
| SCHEMBL31328918 | 0.70 | PKM (0.41) | — | |
| SCHEMBL38651418 | 0.69 | LPL (0.32) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL1300155 | 0.68 | JAK2 (0.41) | JAK2JAK1TYK2JAK3CD274 | |
| SCHEMBL18529005 | 0.67 | AAK1 (0.38) | — | |
| SCHEMBL31473623 | 0.67 | MAP4K1 (0.32) | — | |
| SCHEMBL22579526 | 0.66 | — | — | |
| SCHEMBL23229674 | 0.66 | PGR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304111-A | Synthesis method of darostaamine intermediate | 江苏海悦康医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |