Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978142 | 0.82 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1PIK3R1PIK3CATNK2 | |
| SCHEMBL5525530 | 0.80 | CA2 (0.46) | CA2CA1CA12CA9CA14 | |
| SCHEMBL29196622 | 0.80 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1PIK3R1PIK3CATNK2 | |
| SCHEMBL30918977 | 0.80 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1PIK3R1PIK3CATNK2 | |
| SCHEMBL30918979 | 0.80 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1PIK3R1PIK3CATNK2 | |
| SCHEMBL12450000 | 0.79 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1PIK3R1PIK3CATNK2 | |
| SCHEMBL30885563 | 0.77 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1PIK3R1PIK3CACA2 | |
| SCHEMBL29285095 | 0.77 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1PIK3R1PIK3CACA2 | |
| SCHEMBL4717161 | 0.76 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1PIK3R1PIK3CA | |
| SCHEMBL17673749 | 0.75 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1PIK3R1PIK3CATNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856096-B1 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL MYERS SQUIBB CO (US) | 2010-09-01 | — | — | EP | disclosed |
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |
| US-20060166997-A1 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166997-A1 | Phenylglycinamide derivatives useful as anticoagulants | TFPI, SERPINC1, SERPINE1 | HSP90AA1 1890/4885HSP90AB1 2350/4885PIK3R1 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.