Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ECE1 | P42892 | 4/20 | 0.56 |
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.53 |
| ▸ | ITGAL | P20701 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Golotimod SCHEMBL12966340 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO | |
| Golotimod SCHEMBL14790029 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO | |
| Orilotimod SCHEMBL29379690 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO | |
| Golotimod SCHEMBL726938 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO | |
| Golotimod SCHEMBL726291 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO | |
| Golotimod SCHEMBL12818886 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO | |
| Golotimod SCHEMBL29622906 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO | |
| Orilotimod SCHEMBL733964 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO | |
| Golotimod SCHEMBL1768729 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO | |
| Golotimod SCHEMBL727944 | 0.93 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042286-B1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | CRAGMONT PHARMACEUTICALS LLC (US) | 2010-08-25 | — | — | EP | claimed |
| EP-1042286-B1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | CRAGMONT PHARMACEUTICALS LLC (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-1042286-A1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | Wei, Edward T. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033799-A1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | WEI EDWARD T (US) | 1999-07-08 | — | — | WO | disclosed |