Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549876 | 0.71 | ALDH1A1 (0.45) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL29549875 | 0.71 | ALDH1A1 (0.45) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL23554633 | 0.71 | TDP1 (0.44) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL7756808 | 0.67 | TDP1 (0.44) | TDP1ALDH1A1LMNA | |
| SCHEMBL30422054 | 0.67 | GAA (0.44) | TDP1ALDH1A1RAB9A | |
| SCHEMBL14551282 | 0.67 | GAA (0.44) | TDP1ALDH1A1RAB9A | |
| SCHEMBL28134125 | 0.67 | TDP1 (0.36) | TDP1 | |
| SCHEMBL29549805 | 0.67 | ALDH1A1 (0.41) | TDP1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL23530022 | 0.67 | ALDH1A1 (0.41) | TDP1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL29550468 | 0.67 | TDP1 (0.40) | TDP1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510412-A | Pyridazine derivative and preparation method and application thereof | 贵州大学 | 2024-02-06 | — | — | CN | disclosed |