Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19322345 | 0.77 | CYP1A2 (0.39) | TDP1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23457247 | 0.76 | TDP1 (0.44) | TDP1ALDH1A1PKM | |
| SCHEMBL19244567 | 0.76 | TDP1 (0.44) | TDP1ALDH1A1PKM | |
| SCHEMBL7256443 | 0.73 | TDP1 (0.40) | TDP1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30994052 | 0.73 | TDP1 (0.41) | TDP1CYP3A4ALDH1A1PKM | |
| SCHEMBL3539819 | 0.73 | ERN1 (0.40) | TDP1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL1753088 | 0.70 | CASP1 (0.53) | TDP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18301222 | 0.70 | CYP1A2 (0.40) | TDP1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL14074055 | 0.67 | — | — | |
| SCHEMBL8604799 | 0.67 | ERN1 (0.54) | TDP1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055113-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | HOFFMANN-LA ROCHE INC. (US) | 2026-02-26 | — | — | US | disclosed |
| EP-4568965-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033454-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | US | disclosed |
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | US | disclosed |
| CN-114728927-A | Novel compounds for the diagnosis, treatment and prevention of diseases associated with aggregation of alpha-synuclein | 莫达戈有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-0828870-B1 | SPIN DYEING PROCESS WITH DYEING SALTS | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2001-02-14 | — | — | EP | disclosed |
| US-6043226-A | TREATING BACTERIAL, PARASITIC AND PROTOZOAL INFECTIONS | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |
| CN-1046330-C | Method for preparing and dyeing modified fibre materials | HOECHST AG (DE) | 1999-11-10 | — | — | CN | disclosed |
| US-5938796-A | Alkali system for dyeing cellulosic textiles by padding methods | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1999-08-17 | — | — | US | disclosed |
| US-4647285-A | Process for printing cellulosic fibres with reactive dye and C3-18 aliphatic carboxylate salt fixing agent | CIBA-GEIGY CORPORATION (US) | 1987-03-03 | — | — | US | disclosed |
| CN-85107872-A | The printing method of cellulose fibre (fabric) | — | 1986-07-09 | — | — | CN | disclosed |
| EP-0053743-B1 | REACTIVE DIOXAZINE DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS CONTAINING HYDROXYLE OR AMIDE GROUPS | BAYER AG (DE) | 1986-05-14 | — | — | EP | disclosed |
| US-4588411-A | Long-shelflife print containing reactive dye and alkali acetate pastes and their use | CIBA-GEIGY CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0179019-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1986-04-23 | — | — | EP | disclosed |
| US-4544738-A | FIBER-REACTIVE YELLOW AND ORANGE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
| EP-0131545-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |
| US-4400504-A | DYEING AND PRINTING CELLULOSE AND POLYAMIDE AND-URETHANE FIBERS; TRIAZINE, PYRIDINE AND PYRIMIDINE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| EP-0053743-A2 | Reactive dioxazine dyestuffs, process for their preparation and their use in dyeing and printing fibrous materials containing hydroxyle or amide groups | BAYER AG (DE) | 1982-06-16 | — | — | EP | disclosed |
| US-4118184-A | Stable liquid aqueous composition of a water-soluble fiber-reactive azo dyestuff, containing a buffer substance, the dyestuff having been prepared by diazotization with a nitrite and coupling in the absence of acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260055113-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS, CLIC1 | TDP1 2183/4885CYP1A2 291/4885CYP3A4 601/4885 |
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | RBM17, SF3B1, SF3B5 | TDP1 387/4885CYP1A2 4423/4885CYP3A4 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.