Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30476761 | 0.89 | HDAC6 (0.48) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL23303478 | 0.80 | MAPK1 (0.48) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL23303475 | 0.80 | MAPK1 (0.48) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL29633641 | 0.79 | PTPRA (0.42) | PTPRAHDAC1MAOBKMT2A | |
| SCHEMBL18596979 | 0.79 | PTPRA (0.56) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL16586263 | 0.79 | HDAC6 (0.44) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL29166084 | 0.77 | LMNA (0.47) | SMN1; SMN2FDPSLMNAMEN1KMT2A | |
| SCHEMBL29166040 | 0.76 | NPY5R (0.45) | TSHRALDH1A1MAOB | |
| SCHEMBL29166073 | 0.76 | NPY5R (0.45) | TSHRALDH1A1MAOB | |
| SCHEMBL7168502 | 0.74 | PGR (0.48) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460743-A | Small molecule VE-PTP inhibitors | 曼宁研究公司 | 2024-01-26 | — | — | CN | disclosed |