⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467460 | 0.65 | — | — | |
| SCHEMBL11154028 | 0.63 | — | — | |
| SCHEMBL29581682 | 0.62 | ACHE (0.39) | — | |
| SCHEMBL7443218 | 0.62 | — | — | |
| SCHEMBL6526251 | 0.62 | — | — | |
| SCHEMBL4422067 | 0.62 | — | — | |
| SCHEMBL13863 | 0.62 | — | — | |
| SCHEMBL241682 | 0.62 | — | — | |
| SCHEMBL312460 | 0.62 | — | — | |
| SCHEMBL309070 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973887-B1 | AZA HETEROCYCLICS FOR THE TREATMENT OF MALARIA OR AIDS | IMMUPHARMA FRANCE SA (FR) | 2012-09-19 | — | — | EP | disclosed |
| US-20100291199-A1 | Compositions and Methods For The Treatment and Prevention of Disease | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-11-18 | — | — | US | disclosed |
| US-7777030-B2 | Compositions and methods for the treatment and prevention of disease | Centre National de la Recherge Scientifique (CNRS) (FR) | 2010-08-17 | — | — | US | disclosed |
| EP-1965806-B1 | 1, 3, 5-triazepin-2, 6-diones for the treatment of malaria | IMMUPHARMA FRANCE SA (FR) | 2010-08-11 | — | — | EP | disclosed |
| EP-1965806-B1 | 1, 3, 5-triazepin-2, 6-diones for the treatment of malaria | IMMUPHARMA FRANCE SA (FR) | 2010-08-11 | — | — | EP | disclosed |
| EP-1973887-A1 | AZA HETEROCYCLICS FOR THE TREATMENT OF MALARIA OR AIDS | Immupharma France SA (FR) | 2008-10-01 | — | — | EP | disclosed |
| EP-1965806-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF DISEASE | IMMUPHARMA FRANCE SA (FR) | 2008-09-10 | — | — | EP | disclosed |
| EP-1289968-B1 | CYCLIC UREA COMPOUNDS AND PREPARATION THEREOF | CENTRE NAT RECH SCIENT (FR) | 2008-02-20 | — | — | EP | disclosed |
| US-20080033167-A1 | Compositions and methods for synthesizing heterocyclic therapeutic compounds | UREKA SARL (FR) | 2008-02-07 | — | — | US | disclosed |
| US-20070293469-A1 | Compositions and methods for the treatment and prevention of disease | UREKA SARL (FR) | 2007-12-20 | — | — | US | disclosed |
| WO-2007074170-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF DISEASE | IMMUPHARMA FRANCE SA (FR) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007074171-A1 | AZA HETEROCYCLICS FOR THE TREATMENT OF MALARIA OR AIDS | IMMUPHARMA FRANCE SA (FR) | 2007-07-05 | — | — | WO | disclosed |
| US-7186828-B2 | Cyclic urea compounds and preparation thereof | IMMUPHARMA (FRANCE) SA (FR) | 2007-03-06 | — | — | US | disclosed |
| EP-1640368-A2 | Cyclic ureas and processes for their preparation | The Centre National de la Recherche Scientifique (FR) | 2006-03-29 | — | — | EP | disclosed |
| US-20040044199-A1 | Cyclic urea compounds and preparation thereof | UREKA SARL (FR) | 2004-03-04 | — | — | US | disclosed |
| EP-1289968-A1 | CYCLIC UREA COMPOUNDS AND PREPARATION THEREOF | Centre National De La Recherche Scientifique (FR) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096318-A1 | CYCLIC UREA COMPOUNDS AND PREPARATION THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2001-12-20 | — | — | WO | disclosed |