SCHEMBL29167463

SCHEMBL29167463

OC(F)C(F)F.OCC(F)C(F)F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25499 0.89
SCHEMBL29178040 0.79 ALDH1A1 (0.35) LMNAALDH1A1
SCHEMBL6691818 0.79
SCHEMBL29182313 0.79 LMNA (0.38) LMNAALDH1A1TDP1L3MBTL1
Ethylene Glycol SCHEMBL28236526 0.74 TSHR (0.42) LMNAALDH1A1
SCHEMBL6295288 0.73
SCHEMBL28989865 0.73 THRB (0.35)
SCHEMBL9853 0.73
SCHEMBL28830063 0.71 ALDH1A1 (0.32) LMNAALDH1A1TDP1
SCHEMBL891738 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777189-A Fluorinated phosphate fluorine-containing ester and preparation method thereof 苏州德加能源科技有限公司 2024-03-29 CN disclosed
CN-117136188-A Process for preparing enantiomerically enriched forms of 2- [2- (2-chlorothiazol-5-yl) -2-hydroxyethyl ] sulfanyl-6-hydroxy-3-methyl-5-phenylpyrimidin-4-one by hydrogenation of 2-oxo derivatives in the presence of chiral transition metal catalysts 巴斯夫欧洲公司 2023-11-28 CN disclosed