Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168327 | 0.92 | DGAT2 (0.36) | IDO1TDO2CYP4F2CYP4A11PRMT5 | |
| SCHEMBL20765180 | 0.88 | GAA (0.36) | IDO1TDO2CYP4F2CYP4A11PRMT5 | |
| SCHEMBL31089969 | 0.88 | GAA (0.36) | IDO1TDO2CYP4F2CYP4A11PRMT5 | |
| SCHEMBL14800595 | 0.87 | IDO1 (0.34) | IDO1TDO2CYP4F2CYP4A11PRMT5 | |
| SCHEMBL6508680 | 0.85 | RET (0.32) | IDO1TDO2CYP4F2CYP4A11PRMT5 | |
| SCHEMBL30124206 | 0.85 | RET (0.32) | IDO1TDO2CYP4F2CYP4A11PRMT5 | |
| SCHEMBL26925293 | 0.85 | RET (0.32) | IDO1TDO2CYP4F2CYP4A11PRMT5 | |
| SCHEMBL657359 | 0.85 | ATR (0.34) | IDO1TDO2CYP4F2CYP4A11PRMT5 | |
| SCHEMBL29168244 | 0.84 | LPL (0.36) | IDO1TDO2PRMT5WDR77LPL | |
| SCHEMBL24805042 | 0.83 | BACE1 (0.32) | CYP4F2CYP4A11DGAT2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |