Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TYK2 | P29597 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.32 |
| ▸ | IL1B | P01584 | 3/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168357 | 0.82 | KRAS (0.36) | RXFP1TP53SMN1; SMN2PDE10AKDM4E | |
| SCHEMBL29168452 | 0.77 | LMNA (0.35) | RXFP1TP53TYK2 | |
| SCHEMBL29168384 | 0.75 | RXFP1 (0.33) | RXFP1TP53PDE10AIRAK4 | |
| SCHEMBL29168387 | 0.75 | RXFP1 (0.33) | RXFP1TP53TYK2IRAK4 | |
| SCHEMBL29168410 | 0.70 | KRAS (0.36) | SMN1; SMN2PDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL27186231 | 0.70 | KRAS (0.38) | P2RX7IL1B | |
| SCHEMBL27186233 | 0.70 | KRAS (0.38) | P2RX7IL1B | |
| SCHEMBL29168348 | 0.69 | P2RX7 (0.34) | SMN1; SMN2P2RX7IL1BKDM4EALDH1A1 | |
| SCHEMBL27186887 | 0.69 | KRAS (0.40) | P2RX7IL1B | |
| SCHEMBL27186885 | 0.69 | KRAS (0.40) | P2RX7IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |