Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168332 | 0.79 | KDM4E (0.39) | CFTRKDM4EALDH1A1TSHR | |
| SCHEMBL27186210 | 0.78 | IRAK4 (0.35) | CFTRKDM4EALDH1A1 | |
| SCHEMBL29154699 | 0.74 | SMN1; SMN2 (0.34) | KDM4EALDH1A1TSHR | |
| SCHEMBL29168366 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1 | |
| SCHEMBL27186099 | 0.67 | CFTR (0.35) | CFTRKDM4EALDH1A1TSHR | |
| SCHEMBL30853313 | 0.66 | — | — | |
| SCHEMBL30853365 | 0.65 | BTK (0.39) | — | |
| SCHEMBL29168335 | 0.59 | KDM4E (0.43) | CFTRKDM4EALDH1A1 | |
| SCHEMBL27186173 | 0.58 | ALDH1A1 (0.45) | CFTRKDM4EALDH1A1TSHR | |
| SCHEMBL31186066 | 0.56 | ALDH1A1 (0.42) | CFTRKDM4EALDH1A1TSHRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |