Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738993 | 0.84 | TDP1 (0.32) | KDM4ELMNAALDH1A1HSD17B10KMT2A | |
| SCHEMBL24849927 | 0.75 | ALDH1A1 (0.41) | KDM4EGAAALOX15LMNAALDH1A1 | |
| SCHEMBL24849939 | 0.75 | ALDH1A1 (0.41) | KDM4EGAAALOX15LMNAALDH1A1 | |
| SCHEMBL6206941 | 0.75 | ALDH1A1 (0.48) | KDM4EGAALMNAALDH1A1HPGD | |
| SCHEMBL924151 | 0.72 | ALDH1A1 (0.52) | KDM4EGAALMNAALDH1A1HPGD | |
| SCHEMBL924256 | 0.71 | ALDH1A1 (0.54) | KDM4EGAAALOX15LMNAALDH1A1 | |
| SCHEMBL31313969 | 0.69 | LMNA (0.41) | KDM4EGAALMNAALDH1A1HPGD | |
| SCHEMBL19586331 | 0.68 | ALOX15 (0.44) | ALOX15LMNAALDH1A1HSD17B10TDP1 | |
| SCHEMBL24849974 | 0.68 | ALDH1A1 (0.41) | KDM4EGAALMNAALDH1A1HPGD | |
| SCHEMBL24849905 | 0.68 | ALDH1A1 (0.41) | KDM4EGAALMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117561258-A | Novel substituted tricyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-02-13 | — | — | CN | disclosed |