Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844397 | 0.80 | BTK (0.41) | BTKBRD4CECR2 | |
| SCHEMBL30853313 | 0.77 | — | — | |
| SCHEMBL27186134 | 0.68 | BRD9 (0.41) | BTKBRD4CECR2 | |
| SCHEMBL30853318 | 0.68 | BTK (0.39) | BTKBRD4CECR2PDPK1 | |
| SCHEMBL29168395 | 0.65 | CFTR (0.31) | — | |
| SCHEMBL27186174 | 0.65 | BRD9 (0.40) | BRD4CECR2 | |
| SCHEMBL29168332 | 0.62 | KDM4E (0.39) | — | |
| SCHEMBL29154699 | 0.59 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL16333767 | 0.59 | BTK (0.56) | BTKPDPK1 | |
| SCHEMBL2424952 | 0.59 | BTK (0.56) | BTKPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |