Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | IL1B | P01584 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27186169 | 0.93 | OPRK1 (0.42) | HTR3AMAP4K1OPRK1SMN1; SMN2 | |
| SCHEMBL29168379 | 0.86 | HTR3A (0.41) | HTR3AMAP4K1OPRK1P2RX7IL1B | |
| SCHEMBL29168335 | 0.85 | KDM4E (0.43) | HTR3AMAP4K1PIK3CAP2RX7IL1B | |
| SCHEMBL30720464 | 0.80 | OPRK1 (0.39) | HTR3AMAP4K1OPRK1SMN1; SMN2 | |
| SCHEMBL25431879 | 0.79 | CA12 (0.38) | OPRK1SMN1; SMN2 | |
| SCHEMBL26053358 | 0.79 | OPRK1 (0.38) | OPRK1 | |
| SCHEMBL27186173 | 0.78 | ALDH1A1 (0.45) | OPRK1 | |
| SCHEMBL25433261 | 0.78 | BAZ2B (0.39) | MAP4K1OPRK1 | |
| SCHEMBL29154699 | 0.77 | SMN1; SMN2 (0.34) | OPRK1SMN1; SMN2 | |
| SCHEMBL27190906 | 0.76 | OPRK1 (0.37) | MAP4K1OPRK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |