Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 11/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176931 | 0.92 | HCAR3 (0.38) | HCAR3KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL30087194 | 0.92 | HCAR3 (0.38) | HCAR3KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL30966512 | 0.84 | HCAR3 (0.51) | HCAR3KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL29170127 | 0.82 | HCAR3 (0.53) | HCAR3KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL29170125 | 0.82 | HCAR3 (0.53) | HCAR3KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL29170105 | 0.81 | HCAR3 (0.42) | HCAR3KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL27205213 | 0.80 | HCAR3 (0.47) | HCAR3KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL27176916 | 0.80 | HCAR3 (0.47) | HCAR3KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL30966734 | 0.80 | MAPT (0.43) | HCAR3KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL30087091 | 0.78 | HCAR3 (0.42) | HCAR3KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355517-A | Macrocyclic glucagon-like peptide 1 receptor agonists | 伊莱利利公司 | 2024-01-05 | — | — | CN | disclosed |