Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 11/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176931 | 1.00 | HCAR3 (0.38) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL29170097 | 0.92 | HCAR3 (0.44) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30966734 | 0.88 | MAPT (0.43) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL27176942 | 0.86 | HCAR3 (0.42) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30087091 | 0.86 | HCAR3 (0.42) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL27176783 | 0.86 | KMT2A (0.33) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL31160154 | 0.86 | HCAR3 (0.41) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30966502 | 0.84 | ALDH1A1 (0.44) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30087138 | 0.84 | HCAR3 (0.40) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL27176777 | 0.84 | HCAR3 (0.40) | HCAR3MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341255-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-03-27 | — | — | EP | disclosed |
| WO-2022246019-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2022-11-24 | — | — | WO | disclosed |