Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29170162 | 1.00 | ALDH1A1 (0.37) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL27176958 | 0.91 | HCAR3 (0.39) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL27205413 | 0.91 | HCAR3 (0.39) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL30966520 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL27176844 | 0.86 | TNK2 (0.36) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL27176929 | 0.85 | KDM4E (0.42) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL29170088 | 0.85 | HCAR3 (0.40) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL30087139 | 0.85 | HCAR3 (0.40) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL29170090 | 0.85 | HCAR3 (0.40) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL27176969 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4EKMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355517-A | Macrocyclic glucagon-like peptide 1 receptor agonists | 伊莱利利公司 | 2024-01-05 | — | — | CN | disclosed |