Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27205413 | 1.00 | HCAR3 (0.39) | HCAR3ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL29170162 | 0.91 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL29170164 | 0.91 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL30966515 | 0.88 | ALDH1A1 (0.47) | HCAR3ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL27205213 | 0.84 | HCAR3 (0.47) | HCAR3ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL27176916 | 0.84 | HCAR3 (0.47) | HCAR3ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL29258840 | 0.84 | HCAR3 (0.43) | HCAR3ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL29258838 | 0.84 | HCAR3 (0.43) | HCAR3ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL30966520 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL29157314 | 0.79 | HCAR3 (0.46) | HCAR3ALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341255-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-117355517-A | Macrocyclic glucagon-like peptide 1 receptor agonists | 伊莱利利公司 | 2024-01-05 | — | — | CN | disclosed |