SCHEMBL29170448

SCHEMBL29170448

CC(C)(C)[Si](C)(C)OCCn1cc(COC(N)=O)cn1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
JAK3 P52333 2/20 0.33
LMNA P02545 1/20 0.33
DUT P33316 2/20 0.33
JAK2 O60674 1/20 0.32
JAK1 P23458 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26059803 0.80 DUT (0.35) JAK3DUTL3MBTL1
SCHEMBL24197369 0.78 DUT (0.33) DUT
SCHEMBL1392926 0.76 MEN1 (0.38) JAK3LMNADUTL3MBTL1
SCHEMBL24420592 0.76 L3MBTL1 (0.57) DUTL3MBTL1
SCHEMBL29170425 0.75 NAMPT (0.40) LMNAL3MBTL1
SCHEMBL13860366 0.74 L3MBTL1 (0.43) LMNADUTL3MBTL1
SCHEMBL16769196 0.73 DUT (0.37) JAK3LMNADUT
SCHEMBL27030990 0.72 LMNA (0.42) JAK3LMNAJAK2JAK1L3MBTL1
SCHEMBL25259763 0.72 DUT (0.36) DUTL3MBTL1
SCHEMBL24579070 0.72 DUT (0.36) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117715892-A Quaternary ammonium cation substituted compounds for the treatment of bacterial infections 豪夫迈·罗氏有限公司 2024-03-15 CN disclosed