Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13070297 | 0.84 | THRB (0.37) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL11008165 | 0.81 | THRB (0.35) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL2704293 | 0.79 | THRB (0.39) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL10598952 | 0.79 | NAAA (0.36) | THRB | |
| SCHEMBL11007607 | 0.78 | NAAA (0.38) | THRBMAPTKMT2A | |
| SCHEMBL2924569 | 0.77 | NPC1 (0.34) | THRBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3010206 | 0.77 | KMT2A (0.34) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL3438344 | 0.77 | — | — | |
| SCHEMBL28686318 | 0.75 | THRB (0.39) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL6515441 | 0.74 | PDE4A (0.36) | THRBMAPTPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659023-A | Pyridine acetamide derivative, pharmaceutical composition containing same and medical application of pyridine acetamide derivative | 苏州阿尔脉生物科技有限公司 | 2024-03-08 | — | — | CN | disclosed |