Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6515441 | 0.94 | PDE4A (0.36) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL3980699 | 0.88 | — | — | |
| SCHEMBL19309747 | 0.88 | TRIM24 (0.38) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL13070297 | 0.85 | THRB (0.37) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL11008165 | 0.82 | THRB (0.35) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL10598952 | 0.80 | NAAA (0.36) | THRB | |
| SCHEMBL28686318 | 0.79 | THRB (0.39) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL29170487 | 0.79 | THRB (0.39) | THRBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL11007607 | 0.79 | NAAA (0.38) | THRBMAPTCYP1A2 | |
| SCHEMBL15198299 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069555-A | Synthetic method of substituted phenol | 西安文理学院 | 2023-11-17 | — | — | CN | disclosed |
| EP-1578884-B1 | POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION | NITTO DENKO CORP (JP) | 2013-04-24 | — | — | EP | disclosed |
| EP-2261270-B1 | Polymer, producing method thereof, and photorefractive composition | NITTO DENKO CORP (JP) | 2012-05-09 | — | — | EP | disclosed |
| EP-2261270-A1 | Polymer, producing method thereof, and photorefractive composition | Nitto Denko Corporation (JP) | 2010-12-15 | — | — | EP | disclosed |
| US-20100096603-A1 | OPTICAL DEVICES RESPONSIVE TO NEAR INFRARED LASER AND METHODS OF MODULATING LIGHT | NITTO DENKO CORPORATION (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20090062269-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | MERCK SHARP & DOHME CORP. | 2009-03-05 | — | — | US | disclosed |
| EP-1983993-A2 | NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1874891-A2 | PHOTOREFRACTIVE COMPOSITION | Nitto Denko Corporation (JP) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007092364-A2 | NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2007-08-16 | — | — | WO | disclosed |
| WO-2006112926-A2 | PHOTOREFRACTIVE COMPOSITION | NITTO DENKO CORPORATION (JP) | 2006-10-26 | — | — | WO | disclosed |
| US-20060235163-A1 | Photorefractive composition | NITTO DENKO CORPORATION (JP) | 2006-10-19 | — | — | US | disclosed |
| EP-1664236-A1 | PHOTOREFRACTIVE COMPOSITION | Nitto Denko Corporation (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-1578884-A2 | POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION | NITTO DENKO CORPORATION (JP) | 2005-09-28 | — | — | EP | disclosed |
| US-20050116209-A1 | Image correction device | ARIZONA BOARD OF REGENTS | 2005-06-02 | — | — | US | disclosed |
| WO-2005023962-A1 | PHOTOREFRACTIVE COMPOSITION | NITTO DENKO CORPORATION (JP) | 2005-03-17 | — | — | WO | disclosed |
| US-6867310-B1 | Arylation and vinylation of activated carbons | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-03-15 | — | — | US | disclosed |
| US-20050051758-A1 | Polysiloxane with pendant triphenylamine groups; photoconductive (charge transport) and non-linear optical ability; sensitizers, plasticizers | NITTO DENKO CORPORATION (JP) | 2005-03-10 | — | — | US | disclosed |
| WO-2003085065-A2 | POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION | NITTO DENKO CORPORATION (JP) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062269-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | HCAR1, HCAR2, FFAR1 | THRB 741/4885MAPT 2701/4885PDE4A 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.