SCHEMBL29172249

SCHEMBL29172249

COC(=O)C=C(CCc1cc(F)c(F)cc1F)N[C@H](C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
MEN1 O00255 3/20 0.42
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAPT P10636 1/20 0.40
NPC1 O15118 1/20 0.40
GAA P10253 1/20 0.39
MTOR P42345 1/20 0.39
HPGD P15428 1/20 0.38
GPR139 Q6DWJ6 2/20 0.38
KDM4E B2RXH2 1/20 0.38
DPP4 P27487 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14701601 0.78 CYP3A4 (0.41) KMT2AMEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL18683717 0.78 CYP3A4 (0.41) KMT2AMEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL14688085 0.77 CYP3A4 (0.47) KMT2AMEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL14688086 0.77 CYP3A4 (0.47) KMT2AMEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL10813730 0.76 KMT2A (0.47) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL8306437 0.76 DPP4 (0.38) KMT2AMEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL14687605 0.73 ALDH1A1 (0.45) KMT2AMEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL14687607 0.73 ALDH1A1 (0.45) KMT2AMEN1ALDH1A1CYP3A4CYP2D6
SCHEMBL31011124 0.71 ALDH1A1 (0.41) KMT2AMEN1ALDH1A1CYP2D6CYP2C9
SCHEMBL14687816 0.70 CYP3A4 (0.45) KMT2AMEN1ALDH1A1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117723689-A Method for measuring and analyzing hydrazine hydrate in sitagliptin phosphate-IM 1 浙江江北药业有限公司 2024-03-19 CN disclosed