Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18683717 | 1.00 | CYP3A4 (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19CTSK | |
| SCHEMBL14687605 | 0.91 | ALDH1A1 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19CTSK | |
| SCHEMBL14687607 | 0.91 | ALDH1A1 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19CTSK | |
| SCHEMBL14687295 | 0.91 | ALDH1A1 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19CTSK | |
| SCHEMBL14687297 | 0.91 | ALDH1A1 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19CTSK | |
| SCHEMBL14687816 | 0.87 | CYP3A4 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19CTSK | |
| SCHEMBL14687817 | 0.87 | CYP3A4 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19CTSK | |
| SCHEMBL14688086 | 0.85 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL14688085 | 0.85 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL29172249 | 0.78 | KMT2A (0.42) | CYP3A4CYP2D6CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566843-B1 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | SUN PHARMACEUTICAL IND LTD (IN) | 2017-03-29 | — | — | EP | disclosed |
| US-8471016-B2 | Process for the preparation of chiral beta amino carboxamide derivatives | SUN PHARMACEUTICAL INDUSTRIES LTD. | 2013-06-25 | — | — | US | disclosed |
| US-8471016-B2 | Process for the preparation of chiral beta amino carboxamide derivatives | SUN PHARMACEUTICAL INDUSTRIES LTD. | 2013-06-25 | — | — | US | disclosed |
| US-20130041150-A1 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | SUN PHARMACEUTICAL INDUSTRIES LTD (IN) | 2013-02-14 | — | — | US | disclosed |
| US-20130041150-A1 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | SUN PHARMACEUTICAL INDUSTRIES LTD (IN) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130041150-A1 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | BCAT2, BCAT1, SUCLA2 | CYP3A4 91/4885CYP2D6 380/4885CYP2C9 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.