Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172680 | 1.00 | ITGB3 (0.40) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL29172713 | 0.98 | ITGB3 (0.41) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL29172797 | 0.94 | ITGB3 (0.42) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL29172795 | 0.81 | ITGB3 (0.34) | ITGB3ITGA2BSLC6A1GABRA5GABRB2 | |
| SCHEMBL7550865 | 0.80 | GABRA5 (0.39) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL28644388 | 0.80 | ITGB3 (0.32) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL28794028 | 0.79 | SLC6A1 (0.47) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL28469067 | 0.76 | SLC6A1 (0.50) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL28187856 | 0.76 | SLC6A1 (0.50) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL27166506 | 0.76 | NAMPT (0.53) | ITGB3ITGA2BGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |