Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | TDP2 | O95551 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135882 | 0.97 | CES1 (0.56) | CES1MEN1KMT2APOLBS100A4 | |
| SCHEMBL29402307 | 0.97 | CES1 (0.56) | CES1MEN1KMT2APOLBS100A4 | |
| SCHEMBL6135716 | 0.85 | CES1 (0.47) | CES1MEN1KMT2APOLBS100A4 | |
| Acetic Acid SCHEMBL7085107 | 0.84 | LMNA (0.50) | CES1MEN1KMT2APOLBCASP3 | |
| Acetonitrile SCHEMBL29009230 | 0.84 | CES1 (0.45) | CES1MEN1KMT2APOLBS100A4 | |
| SCHEMBL8045796 | 0.80 | CES1 (0.47) | CES1MEN1KMT2APOLBS100A4 | |
| SCHEMBL10724958 | 0.80 | CES1 (0.47) | CES1MEN1KMT2APOLBS100A4 | |
| SCHEMBL2022462 | 0.77 | POLB (0.64) | CES1MEN1KMT2APOLBS100A4 | |
| SCHEMBL28160078 | 0.77 | POLB (0.64) | CES1MEN1KMT2APOLBS100A4 | |
| SCHEMBL8407065 | 0.75 | ERCC1 (0.63) | CES1MEN1KMT2ACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |