Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.36 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29402307 | 0.83 | CES1 (0.56) | CES1CYP1A2MEN1KMT2APOLB | |
| SCHEMBL135882 | 0.83 | CES1 (0.56) | CES1CYP1A2MEN1KMT2APOLB | |
| SCHEMBL29172805 | 0.80 | CES1 (0.54) | CES1CYP1A2MEN1KMT2APOLB | |
| SCHEMBL10724958 | 0.73 | CES1 (0.47) | CES1CYP1A2MEN1KMT2APOLB | |
| SCHEMBL22651544 | 0.73 | DPP4 (0.43) | CES1DPP4NR1H2NR1H3CYP1A2 | |
| SCHEMBL5454877 | 0.73 | CASP3 (0.59) | CES1DPP4NR1H2NR1H3CYP1A2 | |
| SCHEMBL6135716 | 0.73 | CES1 (0.47) | CES1CYP1A2MEN1KMT2APOLB | |
| SCHEMBL54760 | 0.72 | DPP4 (0.40) | CES1DPP4NR1H2NR1H3CYP1A2 | |
| SCHEMBL31288119 | 0.72 | DPP4 (0.40) | CES1DPP4NR1H2NR1H3CYP1A2 | |
| SCHEMBL30544036 | 0.72 | DPP4 (0.40) | CES1DPP4NR1H2NR1H3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080399-A | REACTING N-CHLOROTHIOPHTHALIMIDE WITH UNSATURATED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | claimed |
| US-4017468-A | IMIDE-MODIFIED TERPOLYMERSSULFUR-CURED RUBBER, TIRES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-04-12 | — | — | US | claimed |
| EP-0989171-A1 | N-halothio-amide-modified elastomers and their application as adhesives for precured elastomeric substrates | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-03-29 | — | — | EP | disclosed |
| US-4080399-A | REACTING N-CHLOROTHIOPHTHALIMIDE WITH UNSATURATED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
| US-4080399-A | REACTING N-CHLOROTHIOPHTHALIMIDE WITH UNSATURATED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
| US-4017468-A | IMIDE-MODIFIED TERPOLYMERSSULFUR-CURED RUBBER, TIRES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-04-12 | — | — | US | disclosed |