Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29173116 | 1.00 | TRPM8 (0.57) | TRPM8L3MBTL1AOC3PARP1TDP1 | |
| SCHEMBL29173105 | 0.86 | TDP1 (0.53) | TRPM8L3MBTL1AOC3TDP1ACHE | |
| SCHEMBL7255555 | 0.86 | AOC3 (0.50) | TRPM8L3MBTL1AOC3PARP1TDP1 | |
| SCHEMBL29173106 | 0.86 | TDP1 (0.53) | TRPM8L3MBTL1AOC3TDP1ACHE | |
| Hydrochloric Acid SCHEMBL7255547 | 0.84 | TDP1 (0.49) | TRPM8L3MBTL1AOC3TDP1ACHE | |
| SCHEMBL11928257 | 0.80 | ALOX5 (0.50) | TRPM8AOC3PARP1CES2CES1 | |
| SCHEMBL25226434 | 0.79 | L3MBTL1 (0.65) | TRPM8L3MBTL1AOC3PARP1CES2 | |
| SCHEMBL5527572 | 0.79 | L3MBTL1 (0.65) | TRPM8L3MBTL1AOC3PARP1CES2 | |
| SCHEMBL6390839 | 0.79 | L3MBTL1 (0.60) | TRPM8L3MBTL1AOC3PARP1CES2 | |
| SCHEMBL11483148 | 0.79 | L3MBTL1 (0.65) | TRPM8L3MBTL1AOC3PARP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480161-A | Novel 2, 3-dihydro-1H-pyrrolo [3,2-b ] pyridine derivatives as sigma ligands | 塔拉森调理公司 | 2024-01-30 | — | — | CN | disclosed |