Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206114 | 1.00 | BTK (0.30) | BTK | |
| SCHEMBL24944457 | 0.91 | EML4 (0.32) | BTK | |
| SCHEMBL30206265 | 0.88 | BTK (0.34) | BTK | |
| SCHEMBL30206107 | 0.87 | CYP1A2 (0.35) | BTK | |
| SCHEMBL29173378 | 0.87 | CYP1A2 (0.35) | BTK | |
| SCHEMBL30206330 | 0.85 | SYK (0.30) | BTK | |
| SCHEMBL29173448 | 0.85 | SYK (0.36) | BTK | |
| SCHEMBL30206336 | 0.85 | SYK (0.36) | BTK | |
| SCHEMBL29173540 | 0.84 | SYK (0.36) | BTK | |
| SCHEMBL30206169 | 0.84 | SYK (0.36) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693503-A | Substituted pyrazine-2-carboxamides as HPK1 inhibitors for the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-03-12 | — | — | CN | disclosed |