Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 8/20 | 0.35 |
| ▸ | JUN | P05412 | 7/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.35 |
| ▸ | RELA | Q04206 | 7/20 | 0.35 |
| ▸ | RORC | P51449 | 7/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.30 |
| ▸ | ATF1 | P18846 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30927637 | 0.83 | ULK1 (0.41) | ULK1 | |
| SCHEMBL29174702 | 0.79 | RPS6KA5 (0.43) | RPS6KA5 | |
| SCHEMBL27503715 | 0.76 | NPC1 (0.41) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL29699125 | 0.76 | SDHB (0.34) | — | |
| SCHEMBL28313446 | 0.73 | PDE3B (0.42) | PIK3CDULK1 | |
| SCHEMBL27229135 | 0.72 | LRRK2 (0.47) | — | |
| SCHEMBL30837013 | 0.72 | LRRK2 (0.47) | — | |
| SCHEMBL30662104 | 0.71 | JUN (0.33) | NFKB1JUNNFKB2RELARPS6KA5 | |
| SCHEMBL21409989 | 0.71 | JUN (0.33) | NFKB1JUNNFKB2RELARPS6KA5 | |
| SCHEMBL30578587 | 0.71 | AR (0.43) | NFKB1JUNNFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745277-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-09-12 | — | — | CN | disclosed |
| CN-116670123-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-08-29 | — | — | CN | disclosed |
| WO-2022134641-A1 | AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |
| WO-2022134642-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |