SCHEMBL29176

SCHEMBL29176

Cc1ccc(P(c2ccc(C)cc2)c2ccc3ccccc3c2-c2c(P(c3ccc(C)cc3)c3ccc(C)cc3)ccc3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
CYP2A6 P11509 5/20 0.38
TSHR P16473 4/20 0.38
CYP1A2 P05177 2/20 0.38
RAB9A P51151 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
NPC1 O15118 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HKDC1 Q2TB90 2/20 0.38
HK1 P19367 1/20 0.37
RAD52 P43351 1/20 0.37
HPRT1 P00492 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361524 1.00 MAPT (0.39) MAPTCYP2A6TSHRCYP1A2RAB9A
Iodide SCHEMBL7946269 0.97 MAPT (0.37) MAPTCYP2A6TSHRCYP1A2RAB9A
Bromide SCHEMBL7948384 0.97 MAPT (0.37) MAPTCYP2A6TSHRCYP1A2RAB9A
Fluoride Ion SCHEMBL7937209 0.97 RAB9A (0.40) MAPTCYP2A6TSHRCYP1A2RAB9A
Bromide SCHEMBL7948386 0.97 MAPT (0.37) MAPTCYP2A6TSHRCYP1A2RAB9A
Hydrochloric Acid SCHEMBL7937215 0.97 RAB9A (0.40) MAPTCYP2A6TSHRCYP1A2RAB9A
SCHEMBL9116348 0.97 MAPT (0.37) MAPTCYP2A6TSHRCYP1A2RAB9A
Hydrochloric Acid SCHEMBL1185945 0.97 MAPT (0.37) MAPTCYP2A6TSHRCYP1A2RAB9A
Iodide SCHEMBL7946268 0.97 MAPT (0.37) MAPTCYP2A6TSHRCYP1A2RAB9A
SCHEMBL18417624 0.97 MAPT (0.37) MAPTCYP2A6TSHRCYP1A2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710422-B1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA CROP PROTECTION AG (CH) 2026-01-07 EP claimed
EP-3856738-B1 PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST QUIM SINTETICA S A (ES) 2025-03-19 EP claimed
US-20240002400-A1 ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES AMGEN INC. (US) 2024-01-04 US claimed
EP-4251604-A1 ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES Amgen Inc. (US) 2023-10-04 EP claimed
US-11591314-B2 Process for preparing tetrahydrocarbazole carboxamide compound BRISTOL-MYERS SQUIBB COMPANY (US) 2023-02-28 US claimed
US-11465977-B2 Process for the preparation of sphingosine-1-phosphate receptor agonist Química Sintética, S.A. (ES) 2022-10-11 US claimed
WO-2022115400-A1 ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES AMGEN INC. (US) 2022-06-02 WO claimed
US-20220033365-A1 PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST Química Sintética, S.A. (ES) 2022-02-03 US claimed
EP-2981560-B1 CURING OF LIQUID THERMOSETTING RESINS REICHHOLD LLC 2 (US) 2021-10-13 EP claimed
EP-3856738-A1 PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST Química Sintética, S.A. (ES) 2021-08-04 EP claimed
EP-0245960-B1 PROCESS FOR PREPARING N-ACYLTETRAHYDROISOQUINOLINE Takasago Perfumery Co., Ltd. (JP) 1992-07-29 EP claimed
EP-0272787-B1 CATALYTIC PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID Takasago International Corporation (JP) 1992-05-06 EP claimed
US-5081310-A PROCESS FOR PREPARING OPTICALLY ACTIVE KETONES TAKASAGO INTERNATIONAL CORPORATION (JP) 1992-01-14 US claimed
US-4962230-A RUTHENIUM-OPTICALLY ACTIVE PHOSPHINE COMPLEX HYDROGENATION CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 1990-10-09 US claimed
US-4851537-A Process for preparing N-acyltetrahydroisoquinoline TAKASAGO PERFUMERY CO., LTD. (JP) 1989-07-25 US claimed
EP-0156607-B1 RHODIUM-PHOSPHINE COMPLEX CATALYST Takasago Perfumery Co., Ltd. (JP) 1988-11-17 EP claimed
EP-0272787-A2 Catalytic production of optically active carboxylic acid Takasago International Corporation (JP) 1988-06-29 EP claimed
EP-0258967-A2 Process for producing optically active alcohols Takasago Perfumery Co., Ltd. (JP) 1988-03-09 EP claimed
US-4604474-A CATALYST FOR ASYMMETRIC HYDROGENATION OR ISOMERIZATION SYNTHESES TAKASAGO PERFUMERY CO., LTD. (JP) 1986-08-05 US claimed
EP-0156607-A2 Rhodium-phosphine complex catalyst Takasago Perfumery Co., Ltd. (JP) 1985-10-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11591314-B2 Process for preparing tetrahydrocarbazole carboxamide compound CYP2C8, CYP3A7, PARP8 MAPT 2849/4885CYP2A6 120/4885TSHR 2283/4885
US-20240002400-A1 ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES MCL1, BAK1, BCL2A1 MAPT 3468/4885CYP2A6 2071/4885TSHR 4359/4885
US-20220033365-A1 PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST S1PR1, S1PR4, S1PR3 MAPT 3610/4885CYP2A6 2431/4885TSHR 237/4885
US-11465977-B2 Process for the preparation of sphingosine-1-phosphate receptor agonist S1PR1, S1PR4, S1PR3 MAPT 3610/4885CYP2A6 2431/4885TSHR 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.