SCHEMBL29176249

SCHEMBL29176249

O=C(C1=CCC(Cl)(I)C=C1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SRD5A2 P31213 1/20 0.35
HPGDS O60760 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
AKR1C3 P42330 1/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPT P10636 3/20 0.32
LMNA P02545 2/20 0.32
RAB9A P51151 2/20 0.32
TSHR P16473 2/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
STAT1 P42224 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156513 0.84 ALDH1A1 (0.42) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL4035522 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL11743114 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL6510163 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL7430914 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27893123 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27661013 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL26630609 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL28643160 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27458451 0.79 ALDH1A1 (0.37) ALDH1A1L3MBTL1ATMTDP1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117769458-A Method for preparing a medium of a substantially monodisperse population of polyarylene ketone or polyarylene sulfide ketone particles, and container comprising said medium 安捷伦科技有限公司 2024-03-26 CN disclosed
CN-117693551-A Method for preparing porous devices from monodisperse populations of poly aryl ketone or poly aryl thioether ketone particles 安捷伦科技有限公司 2024-03-12 CN disclosed
CN-117693542-A Method for preparing monodisperse populations of poly aryl ketone or poly aryl thioether ketone particles 安捷伦科技有限公司 2024-03-12 CN disclosed