SCHEMBL4035522

SCHEMBL4035522

O=C(C1=CCC(O)(Cl)C=C1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SRD5A2 P31213 1/20 0.36
TRPA1 O75762 1/20 0.35
MAPK1 P28482 1/20 0.35
GSK3B P49841 1/20 0.35
HIF1A Q16665 1/20 0.35
HPGDS O60760 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
AKR1C3 P42330 1/20 0.34
TSHR P16473 3/20 0.33
HSD17B10 Q99714 2/20 0.33
USP2 O75604 1/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPT P10636 3/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156513 0.85 ALDH1A1 (0.42) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL11743114 0.84 ALDH1A1 (0.41) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL136599 0.83 ALDH1A1 (0.43) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27661013 0.83 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL6510163 0.83 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL7430914 0.83 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL29176249 0.83 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27893123 0.83 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27513057 0.81 KMT2A (0.35) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL4959091 0.81 ALDH1A1 (0.41) ALDH1A1L3MBTL1ATMTDP1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143331-B Method and production system for refining polyether ketone by supercritical carbon dioxide 江苏亨峰隆新材料有限公司 2024-01-30 CN claimed
CN-117164442-A Preparation method of 4-chloro-4' -hydroxybenzophenone 杭州臻峰科技有限公司 2023-12-05 CN claimed
CN-117143331-A Method and production system for refining polyether ketone by supercritical carbon dioxide 江苏亨峰隆新材料有限公司 2023-12-01 CN claimed
CN-114920637-B Preparation process of 4-chloro-4' -hydroxybenzophenone 江苏科技大学 2023-11-21 CN claimed
CN-110761074-B Environment-friendly low-temperature water-repellent and oil-repellent composition 乳源东阳光氟有限公司 2023-08-08 CN claimed
CN-110483270-B Preparation method for efficient green synthesis of fenofibric acid 杭州新桂实业有限公司 2022-05-20 CN claimed
CN-114213650-A Preparation method of polyaryletherketone with controllable melting point 江苏亨博复合材料有限公司 2022-03-22 CN claimed
CN-107108826-B PEEK and PEEK/PEK copolymer and preparation method thereof 加尔达化学有限公司 2020-03-06 CN claimed
CN-110668928-A Synthesis method of high-purity 4-chloro-4' -hydroxybenzophenone 郎溪李仕化学品有限公司 2020-01-10 CN claimed
CN-110483270-A A kind of preparation method of efficient green synthesis fenofibrate HANGZHOU NEW CHAMPION IND CO LTD 2019-11-22 CN claimed
CN-101605863-A The amine stabiliser of fluoroolefins DU PONT (US) 2009-12-16 CN claimed
CN-101528887-A Epoxides and fluorinated oxiranes stabilizers for fluoroolefins DU PONT (US) 2009-09-09 CN claimed
CN-101528886-A Terpene, terpenoid and fullerene stabilizers for fluoroolefins DU PONT (US) 2009-09-09 CN claimed
CN-101522850-A Thiol and thioether stabilizers for fluoroolefins DU PONT (US) 2009-09-02 CN claimed
CN-101522849-A Phosphorus-containing stabilizers for fluoroolefins DU PONT (US) 2009-09-02 CN claimed
CN-101517032-A Ascorbic acid, terephthalate, or nitromethane stabilizers for fluoroolefins DU PONT (US) 2009-08-26 CN claimed
CN-101511967-A Phenol stabilizers for fluoroolefins DU PONT (US) 2009-08-19 CN claimed
EP-0344688-B1 PROCESS FOR PRODUCING A PHENOLATE AND PROCESS FOR PRODUCING AN AROMATIC POLYETHER KETONE EMPLOYING IT MITSUBISHI KASEI CORPORATION (JP) 1993-08-04 EP claimed
EP-0344688-A2 Process for producing a phenolate and process for producing an aromatic polyether ketone employing it MITSUBISHI KASEI CORPORATION (JP) 1989-12-06 EP claimed
EP-0057503-A1 Production of hydroxy arylophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-08-11 EP claimed