SCHEMBL6510163

SCHEMBL6510163

NC1(Cl)C=CC(C(=O)c2ccccc2)=CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
ATM Q13315 1/20 0.35
SRD5A2 P31213 1/20 0.35
MAPT P10636 4/20 0.35
GAA P10253 1/20 0.35
HPGDS O60760 1/20 0.34
PBRM1 Q86U86 1/20 0.34
KMT2A Q03164 3/20 0.33
HSD17B10 Q99714 3/20 0.33
TSHR P16473 2/20 0.33
MEN1 O00255 2/20 0.33
AKR1C3 P42330 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
PARP1 P09874 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156513 0.87 ALDH1A1 (0.42) ALDH1A1L3MBTL1TDP1ATMSRD5A2
SCHEMBL528382 0.84 ALDH1A1 (0.42) ALDH1A1L3MBTL1TDP1ATMSRD5A2
SCHEMBL27557280 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1TDP1ATMSRD5A2
SCHEMBL11743114 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1TDP1ATMSRD5A2
SCHEMBL4035522 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1TDP1ATMSRD5A2
Benzophenone SCHEMBL28991975 0.83 ALDH1A1 (0.45) ALDH1A1L3MBTL1TDP1ATMSRD5A2
SCHEMBL7430914 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1TDP1ATMSRD5A2
SCHEMBL27620599 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1TDP1ATMSRD5A2
SCHEMBL29176249 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1TDP1ATMSRD5A2
SCHEMBL28271865 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1TDP1ATMSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100364968-C Diphenyl ketone photo initiator containing sulfur and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2008-01-30 CN claimed
CN-1850798-A Diphenyl ketone photo initiator containing sulfur and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-10-25 CN claimed
CN-1850784-A Diphenyl ketone photo initiator containing phenoxy, and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-10-25 CN claimed
CN-1727364-A Photoinitiator of benzophenone containing maleimide base group, and preparation method UNIV SHANGHAI JIAOTONG (CN) 2006-02-01 CN claimed
CN-1058277-C Monoazo acid red dye without carcinogenesis and its synthetic method HUADONG UNIV OF SCIENCES & ENG (CN) 2000-11-08 CN claimed
CN-1178813-A Monoazo acid red dye without carcinogenesis and its synthetic method HUADONG UNIV OF SCIENCES AND E (CN) 1998-04-15 CN claimed
CN-114805133-A Aryl chloroformate preparation method 苏州星日化学有限公司 2022-07-29 CN disclosed
CN-109294457-A Superpower shellproof implosion guard glue film of one kind and preparation method thereof 陈纪霖 2019-02-01 CN disclosed
CN-108276924-A High-transmittance UV-yellowing-resistant hardened film and preparation method thereof 东莞市纳利光学材料有限公司 2018-07-13 CN disclosed
CN-102126994-A Benzophenone hydrazone derivative and preparation method and application thereof SINOCHEM LANTIAN CO LTD 2011-07-20 CN disclosed
CN-100364968-C Diphenyl ketone photo initiator containing sulfur and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2008-01-30 CN disclosed
CN-1907965-A Toluenesulfonamide derivative and insecticidal activity thereof ZHEJIANG CHEM TECH GROUP CO LT (CN) 2007-02-07 CN disclosed
CN-1850798-A Diphenyl ketone photo initiator containing sulfur and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-10-25 CN disclosed
WO-2005037839-A1 NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF ENTOMED (FR) 2005-04-28 WO disclosed
CN-1101391-C Farnesyl transferase inhibiting 2-quinolone derivatives JANSSEN PHARMACEUTICA NV (BE) 2003-02-12 CN disclosed
CN-1058277-C Monoazo acid red dye without carcinogenesis and its synthetic method HUADONG UNIV OF SCIENCES & ENG (CN) 2000-11-08 CN disclosed
CN-1200732-A Farnesyl transferase inhibiting 2-quinolone derivatives JANSSEN PHARMACEUTICA NV (BE) 1998-12-02 CN disclosed
CN-1178813-A Monoazo acid red dye without carcinogenesis and its synthetic method HUADONG UNIV OF SCIENCES AND E (CN) 1998-04-15 CN disclosed
EP-0632017-A1 N-phenyl-2-cyano-3-hydroxy propenamides, their tautomeres and salts, their use as medicaments and compositions containing them ROUSSEL UCLAF (FR) 1995-01-04 EP disclosed
US-4344893-A SUBSTITUTED BENZOPHENONE HYDRAZONES THE BOOTS COMPANY LIMITED (GB) 1982-08-17 US disclosed