Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KATNA1 | O75449 | 1/20 | 0.47 |
| ▸ | MAP3K11 | Q16584 | 6/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.43 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30800088 | 1.00 | KATNA1 (0.47) | KATNA1MAP3K11PTK2STIM1ORAI1 | |
| SCHEMBL29176294 | 0.91 | KATNA1 (0.47) | KATNA1MAP3K11PTK2LRRK2PLK1 | |
| SCHEMBL28475487 | 0.86 | KATNA1 (0.51) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL30800023 | 0.83 | KATNA1 (0.64) | KATNA1MAP3K11LRRK2TUBB4ATUBB | |
| SCHEMBL29176281 | 0.83 | KATNA1 (0.64) | KATNA1MAP3K11LRRK2TUBB4ATUBB | |
| SCHEMBL29176285 | 0.82 | KATNA1 (0.50) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL28469098 | 0.82 | MAP3K11 (0.53) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176283 | 0.81 | KATNA1 (0.52) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL30799989 | 0.81 | KATNA1 (0.52) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176290 | 0.81 | KATNA1 (0.46) | KATNA1MAP3K11LRRK2FYNTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732584-B | Diaryl substituted fused heterocycle compound and preparation method and application thereof in pharmacy | 复旦大学 | 2024-02-27 | — | — | CN | disclosed |