Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KATNA1 | O75449 | 1/20 | 0.46 |
| ▸ | MAP3K11 | Q16584 | 10/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.42 |
| ▸ | MTOR | P42345 | 3/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469098 | 0.88 | MAP3K11 (0.53) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176285 | 0.86 | KATNA1 (0.50) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176283 | 0.85 | KATNA1 (0.52) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL30799989 | 0.85 | KATNA1 (0.52) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176281 | 0.85 | KATNA1 (0.64) | KATNA1MAP3K11LRRK2TUBB4ATUBB | |
| SCHEMBL30800023 | 0.85 | KATNA1 (0.64) | KATNA1MAP3K11LRRK2TUBB4ATUBB | |
| SCHEMBL29176319 | 0.85 | TUBB4A (0.45) | KATNA1MAP3K11LRRK2TUBB4ATUBB | |
| SCHEMBL28475487 | 0.83 | KATNA1 (0.51) | KATNA1MAP3K11LRRK2TP53 | |
| SCHEMBL29176280 | 0.81 | KATNA1 (0.46) | KATNA1MAP3K11LRRK2TUBB4ATUBB | |
| SCHEMBL29176307 | 0.81 | KATNA1 (0.47) | KATNA1MAP3K11FYNLRRK2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732584-B | Diaryl substituted fused heterocycle compound and preparation method and application thereof in pharmacy | 复旦大学 | 2024-02-27 | — | — | CN | disclosed |