Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KATNA1 | O75449 | 1/20 | 0.52 |
| ▸ | MAP3K11 | Q16584 | 9/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29176283 | 1.00 | KATNA1 (0.52) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176285 | 0.89 | KATNA1 (0.50) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176281 | 0.88 | KATNA1 (0.64) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL30800023 | 0.88 | KATNA1 (0.64) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL28469098 | 0.86 | MAP3K11 (0.53) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176290 | 0.85 | KATNA1 (0.46) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL28475487 | 0.85 | KATNA1 (0.51) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176280 | 0.84 | KATNA1 (0.46) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL29176319 | 0.83 | TUBB4A (0.45) | KATNA1MAP3K11LRRK2 | |
| SCHEMBL30800088 | 0.81 | KATNA1 (0.47) | KATNA1MAP3K11LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732584-B | Diaryl substituted fused heterocycle compound and preparation method and application thereof in pharmacy | 复旦大学 | 2024-02-27 | — | — | CN | disclosed |