Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177386 | 0.95 | POLB (0.44) | ALDH1A1MAPTPOLBSMN1; SMN2PARP1 | |
| SCHEMBL28941048 | 0.85 | POLB (0.58) | ALDH1A1POLBPTPN11AOC3KDM4E | |
| SCHEMBL184999 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTPOLBSMN1; SMN2PTPN11 | |
| SCHEMBL186136 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBSMN1; SMN2PTPN11 | |
| SCHEMBL29177328 | 0.79 | UBE2T (0.49) | ALDH1A1MAPTPOLBPARP1KMT2A | |
| SCHEMBL28284732 | 0.76 | UBE2T (0.53) | ALDH1A1MAPTPOLBSMN1; SMN2PARP1 | |
| SCHEMBL29177274 | 0.74 | UBE2T (0.51) | ALDH1A1MAPTPOLBSMN1; SMN2PARP1 | |
| SCHEMBL20917117 | 0.73 | POLB (0.50) | ALDH1A1MAPTPOLBSMN1; SMN2PTPN11 | |
| SCHEMBL4790004 | 0.71 | POLB (0.49) | ALDH1A1MAPTPOLBSMN1; SMN2PTPN11 | |
| SCHEMBL29225190 | 0.71 | KMT2A (0.45) | SMN1; SMN2MEN1KMT2AHDAC6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |