Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30800948 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27168325 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29939886 | 0.82 | ALDH1A1 (0.45) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27168398 | 0.82 | ALDH1A1 (0.45) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11697942 | 0.76 | CTSD (0.47) | TDP1MEN1KMT2ACASR | |
| SCHEMBL23802882 | 0.76 | ADRB1 (0.53) | TDP1ALDH1A1MEN1KMT2AADRB1 | |
| SCHEMBL10878607 | 0.76 | ADRB1 (0.53) | TDP1ALDH1A1MEN1KMT2AADRB1 | |
| SCHEMBL23802883 | 0.76 | ADRB1 (0.53) | TDP1ALDH1A1MEN1KMT2AADRB1 | |
| SCHEMBL10877683 | 0.76 | ADRB1 (0.53) | TDP1ALDH1A1MEN1KMT2AADRB1 | |
| SCHEMBL22287548 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117616030-A | Orexin receptor agonists and uses thereof | 爵士制药爱尔兰有限公司 | 2024-02-27 | — | — | CN | disclosed |