SCHEMBL29178239

SCHEMBL29178239

O=C(O)CC(CC(=O)O)(C(=O)O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
SRD5A2 P31213 2/20 0.46
PTPN1 P18031 2/20 0.44
GSK3B P49841 2/20 0.44
PSEN1 P49768 1/20 0.42
PSEN2 P49810 1/20 0.42
APH1B Q8WW43 1/20 0.42
NCSTN Q92542 1/20 0.42
APH1A Q96BI3 1/20 0.42
PSENEN Q9NZ42 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
EPHX2 P34913 2/20 0.42
MIF P14174 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29154383 0.84 KCNN4 (0.44) CES2CES1PTPN1MIFNPC1
SCHEMBL30781927 0.82 SLC13A5 (0.49) CES2SRD5A2L3MBTL1NR4A2RAB9A
SCHEMBL29154375 0.82 SLC13A5 (0.49) CES2SRD5A2L3MBTL1NR4A2RAB9A
SCHEMBL2387498 0.81 HIF1A (0.57) MIFCYP1A2ALDH1A1TSHR
SCHEMBL29154413 0.80 EPHX2 (0.45) EPHX2
SCHEMBL2388857 0.80 HIF1A (0.43) EPHX2MIFRAB9AALDH1A1TSHR
SCHEMBL12258218 0.80 CYP2C19 (0.42) L3MBTL1MIFNPC1RAB9AALDH1A1
SCHEMBL3355856 0.80 CES2 (0.47) CES2CES1SRD5A2PTPN1GSK3B
SCHEMBL29154377 0.80 SLC13A5 (0.54) SRD5A2EPHX2MIFNPC1RAB9A
SCHEMBL29154384 0.79 NR1H2 (0.43) MIFALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117247317-A Based on CO 2 Method for synthesizing dicarboxylic acid/tricarboxylic acid compound 四川大学 2023-12-19 CN disclosed