Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898859 | 0.88 | MEN1 (0.42) | CES2CES1SRD5A2PTPN1NR4A1 | |
| SCHEMBL5767698 | 0.84 | CES2 (0.47) | CES2ALDH1A1LMNA | |
| SCHEMBL3792532 | 0.82 | NPC1 (0.43) | MEN1KMT2AALDH1A1CYP1A2NPC1 | |
| SCHEMBL28692951 | 0.82 | ESR1 (0.54) | MEN1KMT2AALDH1A1CYP1A2LMNA | |
| SCHEMBL504013 | 0.81 | ALDH1A1 (0.57) | KMT2AALDH1A1CYP1A2LMNAHTT | |
| SCHEMBL2535031 | 0.80 | MIF (0.50) | MEN1KMT2AALDH1A1CYP1A2LMNA | |
| SCHEMBL16290265 | 0.80 | CYP19A1 (0.43) | MEN1KMT2AALDH1A1CYP1A2RAB9A | |
| SCHEMBL29178239 | 0.80 | CES2 (0.47) | CES2CES1SRD5A2PTPN1NR4A1 | |
| SCHEMBL11039437 | 0.80 | CYP1A2 (0.44) | MEN1KMT2AEPHX2ALDH1A1CYP1A2 | |
| Hydrogen Sulfide SCHEMBL27877649 | 0.79 | ALDH1A1 (0.55) | KMT2AALDH1A1CYP1A2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188264-A2 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009035150-A2 | 4-PHENYL-5-HYDROXY-3(2H)-PYRIDAZINONE DERIVATIVES AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |