Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33918 | 0.91 | TSHR (0.62) | TSHRALDH1A1LMNANPC1POLB | |
| Sulfuric Acid SCHEMBL2912572 | 0.87 | NPC1 (0.56) | TSHRALDH1A1LMNANPC1POLB | |
| Sulfuric Acid SCHEMBL2921453 | 0.86 | TSHR (0.58) | TSHRALDH1A1LMNANPC1POLB | |
| SCHEMBL3254682 | 0.83 | TSHR (0.55) | TSHRALDH1A1LMNANPC1POLB | |
| Sulfuric Acid SCHEMBL2923461 | 0.83 | NPBWR1 (0.50) | TSHRLMNANPC1POLBGAA | |
| SCHEMBL4617765 | 0.82 | TSHR (0.54) | TSHRALDH1A1LMNANPC1POLB | |
| Hydrochloric Acid SCHEMBL6755818 | 0.82 | TSHR (0.53) | TSHRALDH1A1LMNANPC1POLB | |
| SCHEMBL6004065 | 0.79 | TSHR (0.50) | TSHRALDH1A1LMNANPC1POLB | |
| SCHEMBL6002740 | 0.79 | TSHR (0.50) | TSHRALDH1A1LMNANPC1POLB | |
| SCHEMBL4802151 | 0.77 | TSHR (0.50) | TSHRALDH1A1LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10639257-B2 | Composition for colouring keratin fibres | BEAUTY & BUSINESS S.P.A. (IT) | 2020-05-05 | — | — | US | claimed |
| US-20190117541-A1 | COMPOSITION FOR COLOURING KERATIN FIBRES | BEAUTY & BUSINESS S.P.A. (IT) | 2019-04-25 | — | — | US | claimed |
| US-9993413-B2 | Keratin fibre dyeing composition | BEAUTY & BUSINESS S.P.A. (IT) | 2018-06-12 | — | — | US | claimed |
| US-20170258695-A1 | KERATIN FIBRE DYEING COMPOSITION | BEAUTY & BUSINESS S.P.A. (IT) | 2017-09-14 | — | — | US | claimed |
| EP-3493878-B1 | COSMETIC COMPOSITION COMPRISING CURED SILICONE MATERIALS | DOW SILICONES CORP (US) | 2025-10-08 | — | — | EP | disclosed |
| EP-4548908-A1 | PERMANENT OXIDATIVE HAIR-COLOURING COMPOSITIONS | Beauty & Business SpA (IT) | 2025-05-07 | — | — | EP | disclosed |
| US-20250134788-A1 | PERMANENT OXIDATIVE HAIR-COLORING COMPOSITIONS | BEAUTY & BUSINESS S.P.A. (IT) | 2025-05-01 | — | — | US | disclosed |
| US-11986547-B2 | Cosmetic composition comprising silicone materials | DOW SILICONES CORPORATION (US) | 2024-05-21 | — | — | US | disclosed |
| CN-117794504-A | Iris root extract, compositions and methods for dermatological use | 捷通国际有限公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-4309742-A1 | HAIR TREATMENT METHOD THAT INCREASES THE BOND DENSITY OF DAMAGED HAIR | Beauty & Business S.p.A. (IT) | 2024-01-24 | — | — | EP | disclosed |
| CN-117426992-A | Hair treatment method for increasing bond density of damaged hair | 美容与商业股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-111432885-B | Cosmetic composition comprising a silicone material | 美国陶氏有机硅公司 | 2023-09-29 | — | — | CN | disclosed |
| EP-2663279-A2 | PERSONAL CARE COMPOSITIONS | Dow Corning Corporation (US) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012095399-A2 | PERSONAL CARE AND HEALTH CARE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2012-07-19 | — | — | WO | disclosed |
| EP-1531784-B1 | PEARLY-LUSTRE COLORING AGENTS FOR KERATIN FIBERS | PROCTER & GAMBLE (US) | 2010-09-08 | — | — | EP | disclosed |
| EP-1531784-A1 | PEARLY-LUSTRE COLORING AGENTS FOR KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-05-25 | — | — | EP | disclosed |
| US-20050081311-A1 | Pearly-lustre coloring agents for keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | US | disclosed |
| WO-2004019895-A1 | PEARLY-LUSTRE COLORING AGENTS FOR KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-11 | — | — | WO | disclosed |
| EP-0692245-B1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | WELLA AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| EP-0692245-A1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | Wella Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050081311-A1 | Pearly-lustre coloring agents for keratin fibers | KRT18, AKR7A2, ELOVL5 | TSHR 2521/4885ALDH1A1 384/4885LMNA 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.