Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 10/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801455 | 0.92 | NPBWR1 (0.54) | NPBWR1ALOX15L3MBTL1MCHR1GLA | |
| Sulfuric Acid SCHEMBL9089708 | 0.85 | MEN1 (0.52) | L3MBTL1GAAMEN1KMT2ACMA1 | |
| Sulfuric Acid SCHEMBL2912572 | 0.85 | NPC1 (0.56) | NPBWR1MCHR1GAANPC1LMNA | |
| Sulfuric Acid SCHEMBL2917846 | 0.83 | TSHR (0.61) | NPBWR1L3MBTL1GAANPC1LMNA | |
| Sulfuric Acid SCHEMBL2921453 | 0.81 | TSHR (0.58) | GAANPC1LMNATSHRPOLB | |
| SCHEMBL3254682 | 0.79 | TSHR (0.55) | GAANPC1LMNATSHRPOLB | |
| SCHEMBL17458965 | 0.79 | NPBWR1 (0.52) | NPBWR1ALOX15MCHR1GLAGAA | |
| SCHEMBL1491119 | 0.79 | TSHR (0.67) | NPBWR1ALOX15L3MBTL1MCHR1GLA | |
| SCHEMBL16014358 | 0.78 | TSHR (0.71) | NPBWR1ALOX15L3MBTL1MCHR1NPC1 | |
| SCHEMBL29049972 | 0.78 | PTPN1 (0.60) | NPBWR1ALOX15L3MBTL1MCHR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531784-B1 | PEARLY-LUSTRE COLORING AGENTS FOR KERATIN FIBERS | PROCTER & GAMBLE (US) | 2010-09-08 | — | — | EP | disclosed |
| EP-1531784-A1 | PEARLY-LUSTRE COLORING AGENTS FOR KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-05-25 | — | — | EP | disclosed |
| US-20050081311-A1 | Pearly-lustre coloring agents for keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | US | disclosed |
| WO-2004019895-A1 | PEARLY-LUSTRE COLORING AGENTS FOR KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-11 | — | — | WO | disclosed |
| US-5534267-A | Composition for the oxidative dyeing of hair containing 4,5-diaminopyrazole derivatives as well as new 4,5-diaminopyrazole derivatives and process for their synthesis | WELLA AKTIENGESELLSCHAFT (DE) | 1996-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050081311-A1 | Pearly-lustre coloring agents for keratin fibers | KRT18, AKR7A2, ELOVL5 | NPBWR1 3410/4885ALOX15 801/4885L3MBTL1 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.