Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24803691 | 0.90 | MMP1 (0.46) | MTNR1AMTNR1BKCNQ4KCNQ5GAA | |
| SCHEMBL6587449 | 0.86 | GAA (0.54) | MTNR1AMTNR1BGAAABL1ALDH1A1 | |
| SCHEMBL12044500 | 0.83 | HTT (0.47) | MTNR1AMTNR1BKCNQ4KCNQ5GAA | |
| SCHEMBL15752675 | 0.83 | PYGL (0.48) | MTNR1AMTNR1BKCNQ4KCNQ5GAA | |
| SCHEMBL7968884 | 0.82 | HTT (0.41) | MTNR1AMTNR1BGAAABL1ALDH1A1 | |
| SCHEMBL19961013 | 0.81 | KCNQ4 (0.42) | MTNR1AMTNR1BKCNQ4KCNQ5GAA | |
| SCHEMBL29180880 | 0.81 | KCNQ4 (0.42) | MTNR1AMTNR1BKCNQ4KCNQ5GAA | |
| SCHEMBL30148584 | 0.80 | GAA (0.44) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20080089 | 0.79 | PPARG (0.48) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL19966996 | 0.79 | MAPT (0.44) | MTNR1AMTNR1BKCNQ4KCNQ5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580836-A | Pyrimidine ring structure derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-02-20 | — | — | CN | disclosed |