Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12044500 | 0.86 | HTT (0.47) | GAAALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL15752675 | 0.86 | PYGL (0.48) | GAAALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL29180821 | 0.86 | MTNR1A (0.42) | GAAALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL7968884 | 0.85 | HTT (0.41) | GAAALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL16064411 | 0.83 | NR1H4 (0.44) | GAANR1H4KMT2APTGDR2 | |
| SCHEMBL19966996 | 0.82 | MAPT (0.44) | GAAALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL20080089 | 0.82 | PPARG (0.48) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL19930248 | 0.81 | MAPT (0.43) | GAAALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL15457550 | 0.80 | EPHX1 (0.57) | GAAALDH1A1MEN1KMT2APKM | |
| SCHEMBL113522 | 0.80 | CA12 (0.53) | ALDH1A1TSHRMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177186-B1 | UREAS AND THEIR USE AS CELL ADHESION MODULATORS | AVENTIS PHARMA LTD (GB) | 2004-03-31 | — | — | EP | disclosed |
| US-6620832-B2 | Inhibitor of alpha 4 beta 1 mediated cell adhesion; treatment for asthma and antiinflammatory | AVENTIS PHARMA LTD. (GB) | 2003-09-16 | — | — | US | disclosed |
| US-20020082255-A1 | Substituted ureas | AVENTIS PHARMA LIMITED (GB) | 2002-06-27 | — | — | US | disclosed |
| EP-1177186-A1 | UREAS AND THEIR USE AS CELL ADHESION MODULATORS | Aventis Pharma Limited (GB) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000068223-A1 | UREAS AND THEIR USE AS CELL ADHESION MODULATORS | AVENTIS PHARMA LIMITED (GB) | 2000-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082255-A1 | Substituted ureas | VCAM1, ITGA1, ITGB1 | GAA 4249/4885ALDH1A1 139/4885TSHR 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.