SCHEMBL29181777

SCHEMBL29181777

CCS(=O)(=O)N(C)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
GPR119 Q8TDV5 13/20 0.47
RECQL P46063 1/20 0.45
EPHX1 P07099 1/20 0.45
STS P08842 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2744779 0.92 CCR2 (0.43) HPGDGPR119RECQLEPHX1STS
SCHEMBL24392051 0.85 GPR119 (0.53) HPGDGPR119RECQLEPHX1STS
SCHEMBL1182635 0.85 GPR119 (0.51) HPGDGPR119RECQLEPHX1
SCHEMBL2763375 0.83 RECQL (0.48) HPGDGPR119RECQLEPHX1
SCHEMBL1830482 0.81 HPGD (0.48) HPGDGPR119RECQLEPHX1
SCHEMBL13811514 0.81 GPR119 (0.52) HPGDGPR119RECQLEPHX1
SCHEMBL4711418 0.80 HPGD (0.55) HPGDGPR119RECQLEPHX1
SCHEMBL24393339 0.80 GPR119 (0.47) HPGDGPR119RECQLEPHX1STS
SCHEMBL15410506 0.79 GPR119 (0.52) HPGDGPR119RECQLEPHX1
SCHEMBL10177808 0.79 GPR119 (0.51) HPGDGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645567-A Chalcone derivative containing piperidine sulfonamide structure, and preparation method and application thereof 贵州大学 2024-03-05 CN disclosed