Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528830 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GPR119USP30DPP4L3MBTL1 | |
| SCHEMBL29182025 | 0.85 | GPR119 (0.38) | ALDH1A1GPR119USP30DPP4L3MBTL1 | |
| SCHEMBL29182028 | 0.85 | GPR119 (0.38) | ALDH1A1GPR119USP30DPP4L3MBTL1 | |
| SCHEMBL29181976 | 0.83 | DPP4 (0.39) | GPR119DPP4DPP8DPP7 | |
| SCHEMBL6528675 | 0.83 | ALDH1A1 (0.40) | ALDH1A1GPR119USP30L3MBTL1TSHR | |
| SCHEMBL6530125 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GPR119USP30DPP4L3MBTL1 | |
| SCHEMBL17069022 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GPR119USP30DPP4L3MBTL1 | |
| SCHEMBL5156918 | 0.75 | HSD17B10 (0.47) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL6527845 | 0.74 | DPP4 (0.61) | ALDH1A1GPR119USP30DPP4L3MBTL1 | |
| SCHEMBL20256229 | 0.74 | HSD17B10 (0.49) | ALDH1A1MEN1KMT2AHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769443-A | Fibroblast activation protein inhibitor and use thereof | 3B制药有限公司 | 2024-03-26 | — | — | CN | disclosed |