Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PDE8B | O95263 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29181968 | 0.83 | ALDH1A1 (0.40) | ALDH1A1GPR119USP30L3MBTL1HSD17B10 | |
| SCHEMBL6528830 | 0.83 | ALDH1A1 (0.40) | ALDH1A1GPR119USP30L3MBTL1HSD17B10 | |
| SCHEMBL13805609 | 0.78 | ALDH1A1 (0.54) | ALDH1A1GPR119L3MBTL1TSHRMEN1 | |
| SCHEMBL24928632 | 0.76 | EPHX2 (0.42) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL4153235 | 0.76 | NPC1 (0.45) | ALDH1A1GPR119USP30L3MBTL1HSD17B10 | |
| SCHEMBL6529234 | 0.76 | HSD17B10 (0.47) | ALDH1A1USP30L3MBTL1HSD17B10TSHR | |
| SCHEMBL22139321 | 0.75 | HSD17B10 (0.49) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL20256229 | 0.75 | HSD17B10 (0.49) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL4143386 | 0.75 | GPR119 (0.47) | GPR119HSD17B10NPC1 | |
| SCHEMBL14641475 | 0.75 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |