Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.57 |
| ▸ | PIK3R1 | P27986 | 14/20 | 0.57 |
| ▸ | MTOR | P42345 | 8/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29183975 | 0.99 | PIK3CA (0.58) | PIK3CAPIK3R1MTORHDAC1PIK3CD | |
| SCHEMBL29183819 | 0.90 | PIK3CA (0.60) | PIK3CAPIK3R1MTORHDAC1PIK3CD | |
| SCHEMBL29183799 | 0.89 | PIK3CA (0.61) | PIK3CAPIK3R1MTORHDAC1PIK3CD | |
| SCHEMBL29183880 | 0.88 | PIK3CA (0.64) | PIK3CAPIK3R1MTORHDAC1PIK3CD | |
| SCHEMBL29184000 | 0.87 | PIK3CA (0.64) | PIK3CAPIK3R1MTORHDAC1PIK3CD | |
| SCHEMBL29183994 | 0.87 | PIK3CA (0.58) | PIK3CAPIK3R1MTORHDAC1PIK3CG | |
| SCHEMBL29183820 | 0.86 | PIK3CA (0.58) | PIK3CAPIK3R1MTOR | |
| SCHEMBL29184046 | 0.85 | PIK3CA (0.64) | PIK3CAPIK3R1MTORPIK3CDPIK3CB | |
| SCHEMBL29183797 | 0.85 | MTOR (0.65) | PIK3CAPIK3R1MTORPIK3CDPIK3CB | |
| SCHEMBL29183995 | 0.84 | DRD2 (0.43) | PIK3CAPIK3R1MTORHDAC1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777042-A | Triazine hydroxamic acid derivative and preparation method and application thereof | 长沙医学院 | 2024-03-29 | — | — | CN | disclosed |